1H-Pyrrolo [2 3-b] pyridine 6-methoxy- (CAS # 896722-53-5)

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6-methoxy-1H-cryrolo [2,3-b] pyridine bụ ngwakọta organic nwere usoro kemịkalụ C9H8N2O. Njirimara ya bụ ndị a:

1. Ọdịdị: 6-methoxy-1H-chrrolo [2,3-b] pyridine enweghị agba na kristal edo edo.

2. ebe agbaze: banyere 105-108 ℃.

3. Ebe esi mmiri: ihe dịka 325 ℃.

4. Solubility: Ọ bụ soluble na organic solvents dị ka chloroform, methanol na dimethyl sulfoxide, na ubé soluble na mmiri.

6-methoxy-1H-yrrolo [2,3-b] pyridine nwere ojiji dị mkpa na nyocha ọgwụ na ọgwụ, dị ka:

1. Ọgwụgwọ ọgwụ: A na-eji ya na nyocha na mmepe nke mgbochi tumor, mgbochi mkpali, mgbochi ọrịa kansa na ọgwụ ndị ọzọ.

2. Ngwakọta kemịkalụ: Dị ka etiti dị mkpa na njikọ nke organic, enwere ike iji ya wuo ihe owuwu ihe ndị dị mgbagwoju anya.

Ụzọ maka ịkwadebe 6-methoxy-1H-cryrolo [2,3-b] pyridine bụ nke kachasị dị ka ndị a:

1. N-methylation mmeghachi omume nke indole: Indole na-emeghachi omume na methyl halide iji mepụta 6-methyl indole, wee meghachi omume na N-methyl vinyl amine iji mepụta 6-methoxy-1H-cryrolo [2,3-b] pyridine.

2. Redox mmeghachi omume nke indole: 6-methoxy-1H-pyridolo [2,3-b] pyridine nwere ike nweta site na imeghachi omume indole na sodium nitrite na tert-butyl peroxide.

Banyere ozi nchekwa, enwere ọmụmụ ole na ole gbasara nsi na ihe ize ndụ nke 6-methoxy-1H-pyridolo [2,3-b] pyridine, yabụ nyocha nchekwa akọwapụtara chọrọ nyocha ọzọ. Mgbe ị na-eme nnwale ma ọ bụ ngwa, a ga-agbaso ọrụ nnwale ziri ezi na usoro nchekwa, zere ịkpọtụrụ anụ ahụ na anya ozugbo, ṅaa ntị na usoro nchebe, ma zere ikuru ikuku ma ọ bụ uzuzu. Ọ bụrụ na ọ dị mkpa, a ga-eji ya na ebe ikuku na-ekpo ọkụ.