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2-Amino-6-bromopyridine (CAS# 19798-81-3) Foto egosipụtara
  • 2-Amino-6-bromopyridine (CAS# 19798-81-3) 1

2-Amino-6-bromopyridine (CAS# 19798-81-3)

Ngwongwo kemịkalụ:

Usoro ihe omimi C5H5BrN2
Molar Mass 173.01
Njupụta 1.710±0.06 g/cm3 (buru amụma)
Ebe Na-agbaze 88-91 Celsius C (ọkụ)
Ebe Boling 273.0± 20.0 Celsius C (buru amụma)
Ebe mgbari 118.9°C
Mmiri Solubility Na-agbaze ntakịrị na mmiri.
Solubility Chloroform (obere), methanol (dị ntakịrị)
Uzuoku nrịbama 0.0059mmHg na 25°C
Ọdịdị Ọcha na ntụ ntụ aja aja
Agba Obere odo ruo nchara nchara
pKa 2.73± 0.24 (buru amụma)
Ọnọdụ Nchekwa Debe n'ebe gbara ọchịchịrị, mechie ya na nkụ, okpomọkụ ụlọ

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2-Amino-6-bromopyridine (CAS# 19798-81-3) Ozi

Nchịkọta 2-amino dochie nitrogen-nwere isii-membered heterocyclic ogige nwere mkpa ngwa na chemical ụlọ ọrụ, dị ka 2-amino -6-Bromopyridine bụ otu n'ime ihe ndị dị mkpa n'ime ọgwụ sịntetik na ugbo chemical ụmụ irighiri ihe, na-eji ọtụtụ ebe na njikọ. nke ngwaahịa sitere n'okike, ọgwụ, ihe ndị na-egbuke egbuke na kemịkalụ dị mma dị iche iche.
Ngwa 2-amino dochie nitrogen-nwere isii membed heterocyclic ogige nwere ihe dị mkpa ngwa na chemical ụlọ ọrụ, dị ka 2-amino -6-Bromopyridine bụ otu n'ime ihe ndị dị mkpa na owuwu na sịntetik ọgwụ na ugbo chemical ụmụ irighiri ihe, na-eji ọtụtụ ebe na njikọ. nke ngwaahịa sitere n'okike, ọgwụ, ihe ndị na-egbuke egbuke na kemịkalụ dị mma dị iche iche.
Nkwadebe Nkwadebe nke 2-amino-6-bromopyridine: Tinye 2-fluoro-6-bromo-pyridine (1mmol), pentamidine hydrochloride (2mmol), sodium tert-butoxide (3mmol), HO (0.5mL) na diethylene glycol dimethyl ether (2.5). ml) na tube mmeghachi omume 25 ml. Emere mmeghachi omume ahụ na 150 ℃ maka awa 24. Mgbe emechara mmeghachi omume ahụ, a na-eme ka ọ dị jụụ na ụlọ okpomọkụ. Tinye 10mL nke ethyl acetate iji mebie mmeghachi omume ahụ, gbakwunye 6mL nke mmiri nnu zuru ezu ka ịsacha, kewaa akụkụ nke organic, wee wepụ mmiri mmiri na ethyl acetate maka ugboro 3 (usoro nke ethyl acetate oge ọ bụla bụ 6mL) ma jikọta organic. oge, tinye sodium sulfate anhydrous ka ọ kpọọ nkụ, wepụ ihe mgbaze gụnyere organic mgbaze na inorganic mgbaze site agụụ distillation, na wee kewaa ihe mgbaze organic site na kọlụm chromatography iji nweta ngwaahịa ezubere iche 2-amino-6-bromopyridine nwere mkpụrụ nke 93%.
jiri intermediates ọgwụ.
maka nhazi nke ọma nke 7-azafindole n'otu ite; maka njikọ nke ọgwụ nje HIV

 

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