2-Bromo-5- (trifluoromethyl) pyridine (CAS # 50488-42-1)

Ngwongwo kemịkalụ:

Usoro ihe omimi	C6H3BrF3N
Molar Mass	225.99
Njupụta	1.707±0.06 g/cm3 (buru amụma)
Ebe Na-agbaze	44-48 Celsius C
Ebe Boling	78 Celsius C
Ebe mgbari	78-81°C/30mm
Solubility	Soluble na methanol na ethanol.
Uzuoku nrịbama	0mmHg na 25ºC
Ọdịdị	agịga edo edo na-egbuke egbuke
pKa	-1?+-.0.10 (buru amụma)
Ọnọdụ Nchekwa	Debe n'ebe gbara ọchịchịrị, mechie ya na nkụ, okpomọkụ ụlọ
Ntụgharị uche	1.572
MDL	MFCD00153086
Njirimara anụ ahụ na kemịkalụ	kristal na-adịghị ọcha
Jiri	Ngwa maka palladium-catalyzed α-arylation nke Refomatsky reagents

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NJ UN	UN 2811 6.1/PG 3
WGK Germany	3
Koodu HS	29333990
Klas Hazard	Iwe
Otu nkwakọ ngwaahịa	Ⅲ

Okwu mmalite

2-Bromo-5- (trifluoromethyl) pyridine (nke a makwaara dị ka BTFP) bụ ngwakọta organic. Ihe na-esonụ bụ mmalite nke ọdịdị ya, ojiji ya, usoro nkwadebe na ozi nchekwa ya:

Ogo:

- Ọdịdị: White siri ike

- arọ molekụla: 206.00 g / mol

- Solubility: BTFP dị mfe soluble na organic solvents (dịka, alcohols, ethers, ketones) ma obere soluble na mmiri.

Jiri:

- Dị ka njikọ nke etiti: BTFP na-ejikarị eme ihe na nkwadebe nke ihe ndị na-emepụta ihe na-emepụta ihe, dị ka ogige pyridine, ogige aromatic, wdg.

- Dị ka ligand: BTFP nwere ike iji dị ka ligand maka metal complexes ma na-etinye aka na mmeghachi omume catalytic dị iche iche na nkwadebe nke ihe ndị na-arụ ọrụ.

- Dị ka a reagent: BTFP na-arụ ọrụ dị mkpa na organic njikọ, dị ka njikọ njikọ, nnọchi mmeghachi omume, na mbelata mmeghachi omume.

Usoro:

2-Bromo-5- (trifluoromethyl) pyridine nwere ike iji usoro ndị a:

1. Gbarie 2-amino-5- (trifluoromethyl) pyridine na ihe mgbaze organic kwesịrị ekwesị, dị ka mmanya ma ọ bụ ketone.

2. Tinye ogige bromine (dịka hydrogen bromide, methyl bromide).

3. Mee mmeghachi omume na okpomọkụ kwesịrị ekwesị na ọnọdụ mkpali.

4. Nyochaa ngwaahịa ma mee crystallization na ịdị ọcha.

Ozi nchekwa:

- BTFP nwere ike sie ike ma ọ bụ kristal na obere okpomọkụ, biko chekwaa na ụlọ okpomọkụ ma zere kristal.

- Yiri gloves nchebe kwesịrị ekwesị na enyo mgbe ị na-arụ ọrụ ka ịzenarị akpụkpọ ahụ na anya.

- Zere ikuru uzuzu ya ma ọ bụ vapors, n'ihi na BTFP nwere ike inwe mmetụta na-akpasu iwe na traktị iku ume.

- Rụtụ aka na ntuziaka nchekwa dị mkpa mgbe ị na-eji ma ọ bụ na-ejikwa BTFP, ma tụfuo ihe mkpofu na ihe mgbaze nke ọma.