2-Chloro-3-fluoro-6-picoline (CAS # 374633-32-6)
Okwu mmalite
Ọdịdị: Ọ na-abụkarị enweghị agba na mmiri na-acha odo odo, njirimara ọdịdị a na-egosi na ọ nwere ike ịdị nro na ọkụ na okpomọkụ, ọ dịkwa mkpa ịme ihe iji zere njikwa ọkụ na okpomọkụ n'oge nchekwa na njem njem, dị ka iji karama iko agba aja aja na-echekwa ya. n'ime ụlọ nkwakọba ihe dị mma iji gbochie imewanye agba na mmebi.
Solubility: Ngwakọta ahụ nwere ezigbo solubility na ihe ndị na-emepụta ihe na-emekarị, dị ka toluene na dichloromethane, na-agbaso ụkpụrụ nke solubility yiri ya, ma nwee mmekọrịta ya na ihe ndị na-edozi ahụ site na akụkụ hydrophobic nke molecule; Otú ọ dị, solubility dị na mmiri dị ala, na njikọ hydrogen siri ike n'etiti ụmụ irighiri mmiri na-esi ike imebi nke ọma site na molecule, na-eme ka ọ sie ike ịgbasa ya.
Ebe na-esi esi esi na njupụta: data esi esi esi nwere njikọ chiri anya na mgbanwe ya ma nwee ike ịnye paramita dị mkpa maka arụ ọrụ dị ka distillation na ịdị ọcha, mana ọ dị nwute na ekpughereghị uru isi ihe a kapịrị ọnụ. Njupụta ya dị ntakịrị elu karịa nke mmiri, na ịghọta njupụta nwere ike inye aka n'ụzọ ziri ezi na-atụle mmekọrịta ngbanwe nke olu na ọrụ nnwale ma ọ bụ usoro mmepụta ihe dị ka nnyefe mmiri na nhazi ziri ezi.
Njirimara kemịkalụ
Mmeghachi omume ngbanwe: Atọm chlorine na atom fluorine dị na molekul bụ saịtị nwere ike imeghachi omume. Na mmeghachi omume nucleophilic ngbanwe, nucleophiles siri ike nwere ike ịwakpo saịtị ebe chlorine na atom fluorine dị, dochie atọm kwekọrọ, ma mepụta pyridine ọhụrụ. Dịka ọmụmaatụ, e jikọtara ya na ụfọdụ nucleophiles nke nwere nitrogen na sọlfọ na-emepụta usoro nke ogige heterocyclic nke nwere nitrogen nwere ihe mgbagwoju anya maka nchọpụta ọgwụ ma ọ bụ nchịkọta ihe.
Mmeghachi omume redox: mgbanaka pyridine n'onwe ya kwụsiri ike, ma mgbe oxidants siri ike, dị ka potassium permanganate na hydrogen peroxide jikọtara ya na ọnọdụ acidic, oxidation nwere ike ime, na-ebute mbibi ma ọ bụ mgbanwe nke usoro mgbanaka pyridine; N'aka nke ọzọ, site na iji ihe na-ebelata ihe kwesịrị ekwesị, dị ka metal hydrides, ọ ga-ekwe omume na hydrogenation nke intramolecular unsaturated bonds.
Nke anọ, usoro njikọ
Ụzọ njikọ a na-ahụkarị bụ ịmalite site na pyridine dị mfe ma jiri nwayọọ nwayọọ wulite ihe a chọrọ site na halogenation na mmeghachi omume fluorination. Ihe mmalite ihe pyridine ogige bụ nke mbụ methylated na-ahọrọ ma na-ebute ìgwè methyl n'otu oge ahụ; Mgbe ahụ, jiri reagents halogenation, dị ka chlorine na mmiri mmiri chlorine, nwere ihe mkpali kwesịrị ekwesị na ọnọdụ mmeghachi omume, iji nweta mmeghe nke atom chlorine; N'ikpeazụ, a na-eji reagents fluorinated, dị ka Selectfluor, iji mee ka ebe a na-achọsi ike nweta 2-chloro-3-fluoro-6-methylpyridine n'ụzọ ziri ezi.
Na-eji
Ngwakọta ọgwụ dị n'etiti: usoro ya pụrụ iche na-ahụ n'anya nke ndị na-ahụ maka ọgwụ na-ahụ maka ọgwụ, ọ bụkwa ihe dị elu nke dị n'etiti maka mmepe nke ọhụrụ antibacterial, antiviral, na antitumor ọgwụ. Ngwongwo eletrọnịkị na nhazi oghere nke mgbanaka pyridine na ihe ndị ha na-anọchi anya nwere ike jikọta kpọmkwem na protein ndị dị na vivo, a na-atụkwa anya na a ga-agbanwe ya ka ọ bụrụ ihe na-arụ ọrụ na-arụ ọrụ nke ọma na-arụ ọrụ nke ọma ma emesịa gbanwee ọtụtụ nzọụkwụ.
Sayensị ihe eji eme ihe: N'ihe gbasara njikọta ihe organic, enwere ike iji ya rụpụta ihe polymer na-arụ ọrụ, ihe fluorescent, wdg, site n'ikike ya iwebata chlorine, atom fluorine na akụkụ pyridine nke ọma, ihe onyinye nwere ọkụ eletrik pụrụ iche na ngwa anya. Njirimara, ma na-akwalite mmepe nke teknụzụ dị oke ọnụ dị ka ihe dị mma na ihe ngosi.
