2′-Deoxy-4′-C-ethynyl-2-fluoroadenosine(CAS#865363-93-5)
Na-ewebata 2′-Deoxy-4′-C-ethynyl-2-fluoroadenosine (CAS:865363-93-5), Analọgụ nucleoside na-agbawa obi nke atọrọ ka ọ gbanwee ngalaba nke ihe ọmụmụ ihe omimi na nyocha ọgwụ. Emebere ogige ọhụrụ a iji welie nghọta nke mmekọrịta nucleic acid na usoro cellular, na-eme ka ọ bụrụ ngwá ọrụ bara uru maka ndị nchọpụta na ndị ọkà mmụta sayensị.
2′-Deoxy-4′-C-ethynyl-2-fluoroadenosine bụ mgbanwe nhazi ya pụrụ iche, nke gụnyere nnọchi ethynyl na fluorine na ọnọdụ 4′ na 2′, n'otu n'otu. Mgbanwe ndị a ọ bụghị naanị na-eme ka nkwụsi ike nke ogige ahụ na bioavailability na-eme ka ọ dịkwuo mma kamakwa ọ na-eme ka ike ya banye n'ime membranes cell, na-enye ohere maka nnyefe na ntinye dị irè karị na usoro ndu dị iche iche.
Analọgụ nucleoside a egosila ikike na-ekwe nkwa na ngwa dị iche iche, gụnyere nyocha nje na mgbochi ọrịa kansa. Ikike ya iṅomi nucleosides eke ka ọ na-egosipụta njirimara biochemical dị iche iche na-eme ka ọ bụrụ ezigbo onye ndoro-ndoro maka mmepe nke ndị na-ahụ maka ọgwụgwọ ọhụrụ. Ndị na-eme nchọpụta nwere ike iji 2'-Deoxy-4'-C-ethynyl-2-fluoroadenosine mụọ RNA na DNA njikọ, nyochaa mmekọrịta enzyme, na inyocha usoro nke omume nke ọgwụ ndị dị adị.
Na mgbakwunye na ngwa nyocha ya, ogige a dịkwa njikere ịrụ ọrụ dị mkpa na mmepe nke usoro ọgwụgwọ ọgbọ ọzọ. Site n'inye nghọta n'ime omume na mmekọrịta nucleic acid, 2'-Deoxy-4'-C-ethynyl-2-fluoroadenosine nwere ike inye aka n'ichepụta ọgwụgwọ dị irè na nke ezubere iche maka ọrịa dị iche iche.
Na nchịkọta, 2′-Deoxy-4′-C-ethynyl-2-fluoroadenosine (CAS:865363-93-5) bụ ihe na-egbu egbu nucleoside analog nke na-enye ohere na-enweghị atụ maka nyocha na mmepe na bayoloji molecular na nkà mmụta ọgwụ. Nabata ọdịnihu nke nchọpụta sayensị site na ngwa a pụrụ iche wee mepee ohere ọhụrụ na mbọ nyocha gị.
