![4-[(4-Hydroxy-2-pyrimidinyl)amino] benzonitrile (CAS# 189956-45-4) Foto egosipụtara](https://cdn.globalso.com/xinchem/44Hydroxy2pyrimidinylaminobenzonitrile.png)
4-[(4-Hydroxy-2-pyrimidinyl) amino] benzonitrile (CAS # 189956-45-4)
4-[(4-Hydroxy-2-pyrimidinyl) amino] benzonitrile(CAS#189956-45-4) Ozi
| LogP | 0.9 na pH6.6 |
| jiri | 4-[(4-hydroxy-2-pyrimidinyl) amino] benzonitrile nwere ike iji dị ka ihe etiti na organic synthesis na a pharmaceutical intermediate, na a pụrụ iji na laabu Organic synthesis usoro na chemical na ọgwụ nnyocha na mmepe usoro. |
| nkwadebe | tụọ 2- (methylthio) pyrimidine -4 (3H) -otu (3g,21mmol) na 4-aminobenzonitrile (2.99g,25mmol) na 50mL gburugburu flask ala ala, nke nitrogen na-echebe, jiri nwayọọ nwayọọ kpoo ọkụ ruo 180 ℃, wee meghachi omume maka 8. awa. Mgbe emechara mmeghachi omume ahụ, a na-agbakwunye 20mL nke acetonitrile maka ọgwụgwọ ultrasonic, filtration, a na-asacha achicha nzacha na acetonitrile, ọ dịghị 4-aminobenzonitrile residue nke TLC na-achọpụta, na ìhè odo siri ike nwetara site na ihicha achicha nzacha bụ 4- ( (4-oxo -1, 6-dihydropyrimidine -2-yl) amino) benzonitrile nwere mkpụrụ. 73.6%. |
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