ALPHA-ISO-METHYLIONONE(CAS#127-51-5)
| Akara egwu | Xi - mgbakasị ahụ |
| Koodu ihe egwu | 43 - Nwere ike ịkpata uche site na kọntaktị akpụkpọ |
| Nkọwapụta nchekwa | S24/25 - Zere kọntaktị na akpụkpọ ahụ na anya. S36/37 - Yiri uwe nchebe kwesịrị ekwesị na uwe aka. |
| NJ UN | UN1230 - klas 3 - PG 2 - methanol, ngwọta |
| WGK Germany | 2 |
| Nsi | GRAS (FEMA). |
Okwu mmalite
ewebata
Ngwakọta nke methyl na ethyl isomethyl violet ketone na methyl na ethyl ortho methyl violet ketone.
okike
Alfa isomethylprednisolone bụ ngwakọta organic. Ọ bụ kristal na-acha odo odo siri ike. N'ime ụlọ okpomọkụ, ọ nwere isi ísì ụtọ pụrụ iche.
Alfa isomethylprednisolone bụ ketone na-esi ísì ụtọ. A na-enweta ya site na mmeghachi omume methylation nke mmanya violet ma kpọọ ya ketone isomethyl violet. Ọdịdị molekụla ya nwere mgbanaka aromatic na otu ketone.
N'ime ụlọ okpomọkụ, ọ siri ike, mana enwere ike ịgbaze ya site na kpo oku. Ọ na-esighi ike na mmiri, mana ọ nwere ike igbari na ụfọdụ ihe mgbaze organic dị ka ethanol na dichloromethane. Ọ na-enwe mmetụta nke ọkụ ma nwee ike nweta mmeghachi omume photolysis n'okpuru irradiation ultraviolet.
N'ihe gbasara akụrụngwa kemịkalụ, α- isomethylprednisolone bụ ihe na-emeghachi omume. Ọ nwere ike nweta mmeghachi omume dịka oxidation, mbelata, mgbakwunye, na nnọchi. Ọ na-emeghachi omume na ụfọdụ reagents electrophilic iji mepụta ngwaahịa mgbakwunye. Enwere ike protonate ya na ọnụnọ acid siri ike. Enwere ike ịtụgharị ya ka ọ bụrụ ketone acid site na mmeghachi omume oxidation.
Usoro mmepụta
Ihe ndị a bụ usoro a na-ahụkarị maka imepụta alfa isomethylprednisolone:
Nkwadebe ihe mbụ: Kwadebe ihe mbụ, gụnyere Isobutyl ketone na Cyclohexanone. Ogige abụọ a bụ ihe dị mkpa maka njikọ nke α - isomethylprednisolone.
Ntọala ọnọdụ mmeghachi omume: Meghachi omume isodecanone na cyclohexanol n'okpuru ọnọdụ kwesịrị ekwesị. Ọnọdụ mmeghachi omume na-emekarị bụ ime mmeghachi omume n'okpuru ọnọdụ acidic, na ihe ndị na-emepụta acid na-ejikarị agụnye sulfuric acid (H2SO4) na phosphoric acid (H3PO4).
Nzọụkwụ mmeghachi omume: Gwakọta ụfọdụ ego nke isodecanone na cyclohexanol, ma tinye ihe na-eme ka acid. Mgbe ahụ, a na-eme mmeghachi omume ahụ na okpomọkụ kwesịrị ekwesị, nke a na-ejikarị eme ihe na okpomọkụ nke 50-70 degrees Celsius. Oge mmeghachi omume na-abụkarị ọtụtụ awa ruo iri iri nke awa.
Nkewa na ịdị ọcha: Mgbe mmeghachi omume ahụ mechara, a na-eme ka ngwaahịa ahụ dị ọcha site na ngwakọta mmeghachi omume site na distillation ma ọ bụ ụzọ nkewa ndị ọzọ.
Crystallization na ihicha: Crystallize na kpochaa ngwaahịa emechara ka ọ nweta ngwaahịa isomethylprednisolone ikpeazụ.
