Boc-L-Glutamic acid 1-benzyl ester (CAS # 30924-93-7)

Okwu mmalite

Boc-L-Glutamic acid 1-benzyl ester (Boc-L-Glutamic acid 1-benzyl ester) bụ ngwakọta organic nke nwere usoro kemịkalụ nke C17H19NO6 yana oke ihe omimi nke 337.34. Ọ bụ ihe siri ike na-acha ọcha, soluble na organic solvents dị ka ethanol, dimethylformamide na chloroform.

A na-ejikarị Boc-L-Glutamic acid 1-benzyl ester eme ihe na njikọ nke ogige peptide. Enwere ike iji ya dị ka onye na-ahụ maka micellar ma ọ bụ otu nchebe iji chebe otu amino acid iji gbochie mmeghachi omume akụkụ na-achọghị na mmeghachi omume kemịkal, ma n'otu oge ahụ nwere ike imeziwanye mkpụrụ. Na mgbakwunye, enwere ike iji ya maka njikọ nke ọgwụ polypeptide na ụmụ irighiri ihe ndị metụtara ya.

Usoro maka ịkwadebe Boc-L-Glutamic acid 1-benzyl ester bụ n'ozuzu iwebata otu nchebe Boc n'ime amino group nke glutamic acid, yana iji benzyl anhydride ester mee mmeghachi omume esterification n'ọnọdụ a. A na-eme mmeghachi omume n'ozuzu n'okpuru nnọpụiche ma ọ bụ ọnọdụ bụ isi ma na-achọkarị oge ụfọdụ iji hụ na mmecha nke mmeghachi omume ahụ. Enwere ike sachaa ngwaahịa a nwetara site na kristal ma ọ bụ usoro nchacha ọzọ.

Banyere ozi nchekwa, nchekwa akọwapụtara nke Boc-L-Glutamic acid 1-benzyl ester chọrọ nyocha na nyocha ọzọ. Agbanyeghị, dị ka onye na-ahụ maka kemịkalụ, ọ nwere ike ịnwe mgbakasị ahụ na nsi. A ga-agbasorịrị usoro ụlọ nyocha kwesịrị ekwesị n'oge a na-akpọtụrụ ma ọ bụ na-eji ya, na a ga-akpachapụ anya nchekwa kwesịrị ekwesị, gụnyere iyi ihe nchebe onwe (dịka G., uwe ụlọ nyocha, ugogbe anya ụlọ nyocha, wdg). N'oge eji ma ọ bụ mkpofu, ekwesịrị ikpochapụ ihe mkpofu nke ọma iji zere mmetọ gburugburu ebe obibi.