BOC-L-Phenylglycine (CAS# 2900-27-8)

Okwu mmalite

N-Boc-L-Phenylglycine bụ ihe na-emepụta ihe na-emepụta site na nhazi nke njikọ kemịkalụ n'etiti amino group (NH2) nke glycine na otu carboxyl (COOH) nke benzoic acid. Nhazi ya nwere otu nchebe (Boc Group), nke bụ otu tert-butoxycarbonyl, nke a na-eji echebe mmeghachi omume nke otu amino.

N-Boc-L-phenylglycine nwere ihe ndị a:

- Ọdịdị: White crystalline siri ike

- Solubility: Soluble na ụfọdụ ihe mgbaze organic, dị ka dimethylformamide (DMF), dichloromethane, wdg.

A na-ejikarị N-Boc-L-phenylglycine mee ihe na mmeghachi omume ọtụtụ nzọụkwụ na njikọ organic, karịsịa maka njikọ nke ogige peptide. Enwere ike igbochi otu nchekwa Boc site na ọnọdụ acid, nke mere na otu amino nwere ike meghachi omume wee mee mmeghachi omume na-esote. A pụkwara iji N-Boc-L-phenylglycine mee ihe dị ka ihe nrụpụta maka owuwu nke ụlọ ọrụ chiral na njikọ peptide.

A na-eme nkwadebe nke N-Boc-L-phenylglycine site na usoro ndị a:

A na-eji benzoic acid emezi glycine iji nweta benzoic acid-glycinate ester.

N'iji mmeghachi omume lithium borotrimethyl ether (LiTMP), benzoic acid-glycinate ester bụ protonated wee meghachi omume na Boc-Cl (tert-butoxycarbonyl chloride) iji nweta N-Boc-L-phenylglycine.

- N-Boc-L-phenylglycine nwere ike na-akpasu anya, akpụkpọ ahụ, na traktị iku ume na ekwesịrị izere ya n'oge eji.

- Ngwa nchedo onwe onye dịka uwe ụlọ nyocha, ugogbe nchekwa, wdg kwesịrị iyi mgbe a na-arụ ọrụ.

- Ekwesịrị ịrụ ya na gburugburu ụlọ nyocha nwere ikuku nke ọma.

- Zere kọntaktị na oxidants na acid siri ike mgbe ị na-echekwa ya.

- Ọ bụrụ na iloro ma ọ bụ kuruo ume, chọọ nlekọta ahụike ozugbo, weta akpa nke ogige ahụ, ma nye dọkịta ozi nchekwa dị mkpa.