Boc-L-Tyrosine methyl ester (CAS# 4326-36-7)

Okwu mmalite

N-Boc-L-Tyrosine Methyl Ester bụ ngwakọta kemịkal aha ya bụ N-tert-butoxycarbonyl-L-tyrosine methyl ester. Njirimara ya bụ ndị a:

1. Ọdịdị: ọcha na-acha ntụ ntụ crystalline siri ike;

5. Solubility: soluble na organic solvents dị ka ethanol na dimethylformamide (DMF), insoluble na mmiri.

A na-ejikarị N-Boc-L-tyrosine methyl ester eme ihe na njikọ organic iji chebe amino acid na njikọ nke ogige polypeptide. A na-ejikarị ya dị ka otu nchebe nke L-tyrosine iji gbochie mmeghachi omume na-enweghị isi na mmeghachi omume site na ime. Ozugbo mmeghachi omume ahụ zuru oke, enwere ike iwepụ otu nchebe n'okpuru ọnọdụ kwesịrị ekwesị iji nweta ngwaahịa ezubere iche.

Usoro nkwadebe nke N-Boc-L-tyrosine methyl ester na-agụnyekarị usoro ndị a:

1. igbari L-tyrosine na dimethylformamide (DMF);

2. Tinye sodium carbonate iji kpochapụ otu carboxyl nke tyrosine;

3. Methanol na methyl carbonate (MeOCOCl) na-agbakwunye na ngwakọta mmeghachi omume iji mepụta N-Boc-L-tyrosine methyl ester. A na-eme mmeghachi omume ahụ na obere okpomọkụ, a na-ejikwa oke nke methyl carbonate mee ihe iji hụ na mmeghachi omume ahụ na-aga.

N-Boc-L-tyrosine methyl ester kwụsiri ike, mana ọ ka kwesịrị iji nlezianya mee ya. Ihe a bụ ozi nchekwa izugbe:

1. Zere kọntaktị na akpụkpọ ahụ na anya: A ga-eyi uwe nchebe kwesịrị ekwesị na enyo enyo iji zere kọntaktị kpọmkwem na ogige ahụ;

2. Zere iku ume: Ekwesịrị ijide n'aka na ikuku ikuku dị mma na gburugburu ebe a na-arụ ọrụ iji gbochie ikuku ikuku;

3. Nchekwa: Ekwesịrị ịchekwa ya na ebe dị jụụ, ebe akọrọ ma zere kọntaktị na oxygen, acid siri ike, ma ọ bụ ntọala siri ike.

N'ozuzu, N-Boc-L-tyrosine methyl ester bụ ihe dị mkpa n'etiti na organic synthesis na-arụ ọrụ dị mkpa na njikọ nke peptide ogige. Ekwesịrị ilebara anya maka ọrụ nchekwa mgbe eji na njikwa.