Cbz-L-Glutamic acid 1-benzyl ester (CAS# 3705-42-8)

Okwu mmalite

Z-Glu-OBzl (Z-Glu-OBzl) bụ ngwakọta organic a na-ejikarị dịka otu nchekwa maka amino acid. Nke a bụ nkọwa nke njirimara, ojiji, nkwadebe na ozi nchekwa nke ogige ahụ:

Ọdịdị:

- Usoro ihe omimi: C17H17NO4

-Arọ molekụla: 303.32g/mol

- Ọdịdị: White crystalline ntụ ntụ

- Ebe mgbaze: 84-85°C

-Solubility: Soluble na organic solvents dị ka dimethyl sulfoxide na dimethylformamide

- Enwere ike wepu otu nchekwa Cbz site na palladium hydride catalyst n'okpuru ọnọdụ acid

Jiri:

Z-Glu-OBzl bụ otu nchebe nke glutamic acid (Glu), nke enwere ike iji na njikọ nke amino acid, polypeptides na protein.

-Dị ka otu nchebe maka amino acids na synthetic organic compound, ọ nwere ike ichebe otu amine nke glutamic acid, gbochie ya ka ọ ghara imetụta ya site na mmeghachi omume na-enweghị isi, ma mee ka ọ dị mfe iwepụ mgbe ọ dị mkpa.

Ụzọ nkwadebe:

-Nkwadebe nke Z-Glu-OBzl na-agụnyekarị usoro ọtụtụ nzọụkwụ na-agụnye usoro mmeghachi omume kemịkal. Otu n'ime ụzọ ndị a na-ahụkarị bụ ibu ụzọ kpuchido otu carboxyl nke glutamic acid dị ka t-butoxycarbonyl ester (Boc) wee chebe otu amino dị ka Cbz. N'ikpeazụ, ngwaahịa a chọrọ Z-Glu-OBzl na-etolite site na mmeghachi omume na benzyl chloroformate.

Ozi nchekwa:

- Z-Glu-OBzl kwesịrị ka a na-emeso ya dị ka ogige na-akpasu iwe ma zere kọntaktị kpọmkwem na akpụkpọ ahụ na anya.

-Mgbe ejiri ya na ụlọ nyocha, a ga-agbaso usoro nchekwa ziri ezi, gụnyere iyi mkpuchi mkpuchi, uwe aka na uwe ụlọ nyocha.

-Ekwesịrị ịzere inhalation ma ọ bụ ntinye nke ogige ahụ ma mee ihe mgbochi ọkụ na mgbawa n'oge nchekwa.

-Ekwesịrị itinye ogige ahụ na ebe ikuku na-ekpo ọkụ n'oge nhazi, ma kpochapu ihe mkpofu nke ọma dịka iwu obodo si dị.