FMOC-Arg(Pbf) -OH (CAS# 154445-77-9)
Ihe ize ndụ na Nchekwa
| Akara egwu | Xi - mgbakasị ahụ |
| Koodu ihe egwu | 36/37/38 - na-akpasu iwe na anya, usoro iku ume na akpụkpọ ahụ. |
| Nkọwapụta nchekwa | S26 - N'ihe banyere kọntaktị na anya, kpochaa ozugbo na ọtụtụ mmiri ma chọọ ndụmọdụ ahụike. S36 - Yiri uwe nchebe kwesịrị ekwesị. |
| WGK Germany | 1 |
| Koodu HS | 2935 90 90 |
| Klas Hazard | Iwe |
Okwu mmalite
Otu nchekwa FMOC bụ otu nchekwa amino acid nke a na-ejikarị na-echekwa otu amino arụ ọrụ nke arginine. Ihe na-esonụ bụ mmalite nke ụfọdụ njirimara, ojiji, ụzọ nkwadebe, na ozi nchekwa nke Fmoc-Protective Radical:
Ogo:
Otu na-echekwa FMOC bụ otu nchebe mbughari na-echekwa otu amino amino. Ọ nwere ike meghachi omume na otu amino dị na arginine site na mmeghachi omume esterification iji mepụta Fmoc-arginine ester, iji nweta ebumnuche nke ichekwa otu amino. Enwere otu ndị na-esi ísì ụtọ na molekul Fmoc-echebe nke na-enweta ọkụ UV ike, nke na-enye ohere iwepụ Fmoc-protective otu site na UV irradiation ma ọ bụ ụzọ kemịkalụ.
Jiri:
A na-eji otu ndị na-echekwa FMOC eme ihe na njikọ peptide na njikọ siri ike. Ọ nwere ike ichekwa otu amino arginine nke ọma iji gbochie mmeghachi omume akụkụ ya n'oge njikọ. Na njikọ peptide, otu Fmoc-echebe nwere ike wepu ya site na ọnọdụ alkaline, na-ekwe ka njikọ nke polypeptides gaa n'ihu.
Usoro:
Enwere ike ịkwadebe otu Fmoc-echebe site na mmeghachi omume nke Fmoc-Cl na arginine. Fmoc-Cl bụ reagent siri ike acid nke na-emeghachi omume na otu amino dị na arginine iji mepụta Fmoc-arginine ester. A na-emekarị mmeghachi omume ahụ na ethanol na ụlọ okpomọkụ na okpomọkụ bat.
Ozi nchekwa:
FMOC-Protective Radicals dị mma iji n'okpuru ọnọdụ ụlọ nyocha nkịtị, mana ekwesịrị iburu n'uche ihe ndị a:
- FMOC-CL bụ ihe na-akpasu iwe na nke na-egbu egbu, ekwesịrị ịkpachara anya ka ị ghara ịkpọtụrụ akpụkpọ ahụ, iku ume ma ọ bụ ingestion. Na-arụ ọrụ na mpaghara ikuku nke ọma ma yikwasị akụrụngwa nchedo onwe onye kwesịrị ekwesị.
- FMOC-Protective Base nwere akụrụngwa nke nnabata siri ike nke ụzarị ultraviolet, yabụ ekwesịrị ịkpachara anya iji gbochie ịkpọtụrụ anụ ahụ na anya ozugbo, ma zere isi iyi ọkụ siri ike.
- A na-ejikarị nchebe acid hydrolysis siri ike dị ka pentafluorophenylcarboxylic acid (TFA) n'oge mwepụ nke Fmoc-protective otu, na ọ dị mkpa ka ị mara na vepo nke TFA nwere ike imebi, ya mere ọ dị mkpa iji rụọ ọrụ na nke ọma. mpaghara ventilashị.
