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Levodopa (CAS# 59-92-7) Foto egosipụtara
  • Levodopa (CAS# 59-92-7) 1

Levodopa (CAS# 59-92-7)

Ngwongwo kemịkalụ:

Usoro ihe omimi C9H11NO4
Molar Mass 197.19
Njupụta 1.3075 (atụmatụ siri ike)
Ebe Na-agbaze 276-278 Celsius C (ọkụ)
Ebe Boling 334.28C (atụmatụ siri ike)
Ntụgharị pụrụ iche(α) -11.7º (c=5.3, 1N HCl)
Ebe mgbari 225°C
Mmiri Solubility Na-agbaze ntakịrị na mmiri, gbanye hydrochloric acid na formic acid. Na-adịghị ike na ethanol.
Solubility Ọ dị mfe soluble na dilute hydrochloric acid na formic acid, soluble n'ime mmiri, nke na-adịghị edozi na ethanol, benzene, chloroform na ethyl acetate.
Uzuoku nrịbama 7.97E-09mmHg na 25°C
Ọdịdị Uzuzu crystalline ọcha ruo na mmiri ara ehi
Agba Ọcha ruo ude
Merck 14,5464
BRN 2215169
pKa 2.32 (na 25 ℃)
Ọnọdụ Nchekwa 2-8 Celsius C
Nkwụsi ike Kwụsie ike. Ekwekọrịtaghị na ndị ọrụ oxidizing siri ike. Ìhè na ikuku mmetụta.
Mmetụta Na-enwe mmetụta maka ọkụ na ikuku
Ntụgharị uche -12 Celsius (C=5, 1mol/LH
MDL MFCD00002598
Njirimara anụ ahụ na kemịkalụ ebe mgbaze 295°C
kpọmkwem ntụgharị anya anya -11.7 Celsius (c = 5.3, 1N HCl)
Jiri Ọgwụ dị irè maka ọgwụgwọ ahụ mkpọnwụ nke ujo, nke a na-ejikarị maka ọrịa Parkinson, wdg

Nkọwa ngwaahịa

Mkpado ngwaahịa

Akara egwu Xn - na-emerụ ahụ
Koodu ihe egwu R22 - na-emerụ ma ọ bụrụ na iloro ya
R36 / 37/38 - na-akpasu iwe na anya, usoro iku ume na akpụkpọ ahụ.
R20/21/22 - na-emerụ ahụ site na iku ume, na kọntaktị na akpụkpọ ahụ ma ọ bụrụ na loro ya.
Nkọwapụta nchekwa S26 - N'ihe banyere kọntaktị na anya, kpochaa ozugbo na ọtụtụ mmiri ma chọọ ndụmọdụ ahụike.
S36 - Yiri uwe nchebe kwesịrị ekwesị.
S24/25 - Zere kọntaktị na akpụkpọ ahụ na anya.
WGK Germany 3
RTECS AY5600000
FLUKA BRAND F CODES 10-23
TSCA Ee
Koodu HS 29225090
Nsi LD50 na ụmụ oke (mg / kg): 3650 ± 327 okwu ọnụ, 1140 ± 66 ip, 450 ± 42 iv,> 400 sc; n'ime nwoke, oke nwanyị (mg/kg):>3000,>3000 ọnụ; 624, 663 ip; > 1500,> 1500 sc (Clark)

 

Okwu mmalite

Mmetụta ọgwụ: ọgwụ mgbochi egwu mkpọnwụ. Ọ na-abanye n'anụ ahụ nke ụbụrụ site na mgbochi ụbụrụ ọbara, ma decarboxylated site na dopa decarboxylase ma gbanwee na dopamine, nke na-arụ ọrụ. A na-eji ya eme ihe maka ahụ mkpọnwụ nke mbụ na ịma jijiji na ọrịa mkpọnwụ ahụ nke na-abụghị nke ọgwụ kpatara. Ọ na-enwe mmetụta dị mma na ndị agadi na ndị dị nwayọọ, ndị siri ike ma ọ bụ ndị dara ogbenye.

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