N-Cbz-D-Tryptophan (CAS# 2279-15-4)

Okwu mmalite

N(^ a)-Benzyloxycarbonyl-D-tryptophan (N(^ a)-Benzyloxycarbonyl-D-tryptophan) bụ kemịkalụ, nke a makwaara dị ka CBZ-D-Trp. Nke a bụ nkọwa nke ọdịdị ya, ojiji ya, nhazi ya na ozi nchekwa:

Ọdịdị:

N(^ a)-Benzyloxycarbonyl-D-tryptophan bụ kristal siri ike na-acha ọcha ma na-acha odo odo. Ọ kwụsiri ike na ụlọ okpomọkụ ma enwere ike ịchekwa ya ogologo oge n'okpuru ọnọdụ ikuku. Ọ bụ ihe a na-adịghị ahụkebe na mmiri, mana ọ na-agbaze na ụfọdụ ihe mgbaze organic dị ka methanol na dimethyl sulfoxide.

Jiri:

N (^ a) -Benzyloxycarbonyl-D-tryptophan na-ejikarị dị ka ndị na-echebe otu na organic synthesis, karịsịa na chemical peptide synthesis. Isi ojiji ya bụ dị ka mwepụta nke amino asịd maka njikọ nke kpọmkwem modul na polypeptide ma ọ bụ protein agbụ. Ọ nwere ike ịrụ ọrụ dị mkpa na njikọ nke ọgwụ ọhụrụ n'ụzọ dị otú a.

Usoro:

Nkwadebe nke N (^ a) -Benzyloxycarbonyl-D-tryptophan na-emekarị site na njikọ kemịkal. Nke mbụ, a na-emeghachi omume mmanya benzyl na carbon dioxide iji mepụta benzyloxycarboxylic acid, emesia amino acid tryptophan na benzyloxycarboxylic acid na-esterified iji nweta ngwaahịa CBZ-D-Trp. Mmeghachi omume na-achọ enyemaka nke ụfọdụ organic catalysts na ihe mgbaze.

Ozi nchekwa:

N(^ a)-Benzyloxycarbonyl-D-tryptophan nwere ozi nchekwa nwere oke, mana dabere na ozi dịnụ, a na-ewerekarị ya dị ka ihe na-egbu egbu. Mkpughe ogologo oge ma ọ bụ ikpughe oke nwere ike inwe mmetụta ahụike na-adịghị mma. Ya mere, a ga-emerịrị usoro nchekwa kwesịrị ekwesị mgbe ị na-eji, na-echekwa na ijikwa ogige a, gụnyere iyi ngwá ọrụ nchedo onwe onye kwesịrị ekwesị na njikwa na gburugburu ikuku ikuku. N'otu oge ahụ, ọ dị mkpa ịgbaso usoro ọrụ nchekwa dị mkpa na ụzọ mkpofu.

Biko mara na isiokwu a bụ naanị nchịkọta nke ogige a na-ajụ, yana ngwa ngwa na nyocha ihe ize ndụ kwesịrị ime na gburugburu ụlọ nyocha. Tupu iji ihe ọ bụla kemịkal, biko gbaa mbọ hụ na ị ga-amụ ozi dị mkpa n'ụzọ zuru ezu wee kpọtụrụ ọkachamara n'ihu.