NN-Bis 9-fluorenylmethyloxycarbonyl-L-histidine CAS 98929-98-7

Nkọwapụta nchekwa	S22 - Ekula uzuzu. S24/25 - Zere kọntaktị na akpụkpọ ahụ na anya.
Koodu HS	29242990

N (alpha), N (im) -di-fmoc-L-histidine (N (alpha), N (im) -di-fmoc-L-histidine) bụ ngwakọta enwetara site na mmeghachi omume kemịkalụ nke 9-fluorenecinol na L. - histidine. Usoro kemịkalụ ya bụ C42H38N4O8 na mkpokọta molekul ya bụ 722.78g/mol.N (alpha), N (im) -di-fmoc-L-histidine bụ ngwakọta nke na-echebe amino acid na nke a na-ejikarị eme ihe na njikọ organic na mmeghachi omume biochemical. . A na-ejikarị ya ahazi nhazi protein na ọrụ ya, yana ịgbasa ma melite ngwa ngwa nke eriri polypeptide. A na-eji onyinye a eme ihe n'ọtụtụ usoro nhazi usoro siri ike maka ịmegharị N-terminus na histidine residues nke peptide na protein ụmụ irighiri ihe.

Usoro nke ịkwadebe N(alpha),N(im) -di-fmoc-L-histidine na-agụnyekarị nzọụkwụ atọ. Nke mbụ, ethylene glycol dimethyl ether na diazotoluene meghachiri omume n'okpuru catalysis nke cuprous chloride iji mepụta 9-fluorenmethanol. Mgbe ahụ, 9-fluorenecinol na L-histidine na-emeghachi omume n'okpuru ọnọdụ acidic iji nweta N (alpha), N (im) -di-fmoc-L-histidine. N'ikpeazụ, a na-enweta ngwaahịa dị ọcha site na kristal na usoro nchacha.

Banyere ozi nchekwa, N (alpha), N (im) - Enweghị ọtụtụ akụkọ nyocha dị mkpa gbasara nchekwa dị iche iche nke di-fmoc-L-histidine, yabụ achọrọ ịkpachara anya. Mgbe a na-eji ya n'ụlọ nyocha, ekwesịrị ịme usoro nchekwa kwesịrị ekwesị, gụnyere iyiri ngwa nchebe kwesịrị ekwesị, dị ka uwe ụlọ nyocha na ugogbe anya, na izere kọntaktị na akpụkpọ ahụ na anya. N'otu oge ahụ, a ga-echekwa ya n'ime akpa akọrọ, ikuku na-ekpo ọkụ na nke mechiri emechi, pụọ na ọkụ na ihe ndị na-ere ọkụ. Maka ozi nchekwa zuru ezu, a na-atụ aro ka ị kpọtụrụ akwụkwọ ndị dị mkpa ma ọ bụ kpọtụrụ ọkachamara.