Mpaghara ọgwụ na-aga n'ihu na-aga n'ihu, yana ogige ndị akọwapụtara na-enweta nlebara anya maka ikike ọgwụgwọ ha na akụrụngwa kemịkal pụrụ iche. Otu n'ime ogige, 3- (trifluoromethyl) phenylacetic acid (CAS351-35-9), adọtala uche na United States na Switzerland. Isiokwu a na-enyocha ihe ndị dị ugbu a, mgbanwe ahịa ahịa na atụmanya ọdịnihu nke onyinye a na ahịa abụọ a dị mkpa.
Nchịkọta ahịa
3- (Trifluoromethyl) phenylacetic acid bụ ihe dị n'etiti etiti dị iche iche na-eji na njikọ nke ọgwụ dị iche iche, karịsịa na mmepe nke ọgwụ mgbochi mkpali na analgesic. Otu trifluoromethyl pụrụ iche na-eme ka lipophilicity na nkwụsi ike nke ihe mejupụtara ya na-eme ka ọ bụrụ nhọrọ mara mma maka ndị na-emepụta ọgwụ. United States na Switzerland, bụ ndị a ma ama maka ụlọ ọrụ na-emepụta ọgwụ siri ike, bụ ndị na-ebute ụzọ n'ịzụlite ogige ahụ.
Na United States, a na-eji ọkwa dị elu nke ihe ọhụrụ na itinye ego nyocha mara ahịa ọgwụ. Ọnụnọ nke ndị isi ụlọ ọrụ na-emepụta ọgwụ na usoro iwu siri ike nke FDA na-akwado mmepe na ịzụ ahịa ọgwụ ọhụrụ. Achọ maka 3- (trifluoromethyl) phenylacetic acid na-atụ anya na ọ ga-abawanye ka ụlọ ọrụ na-achọ ịmepụta ọgwụgwọ dị irè karị na mmetụta dị nta.
N'aka nke ọzọ, a maara Switzerland maka mmepụta ọgwụ dị elu na ike nyocha. Obodo a nwere ọtụtụ ụlọ ọrụ na-ahụ maka ọgwụ na-etinye nnukwu ego na nyocha na mmepe. Ahịa Switzerland na-etinye uche pụrụ iche na mmepe nke ọgwụ ziri ezi na usoro ọgwụgwọ ezubere iche, nke ogige ndị dị ka 3- (trifluoromethyl) phenylacetic acid nwere ike ịrụ ọrụ dị mkpa.
Gburugburu ebe nchịkwa
United States na Switzerland abụọ nwere usoro iwu siri ike maka ụlọ ọrụ ọgwụ. Na United States, FDA na-ahụ maka usoro nnabata maka ọgwụ ọhụrụ ma hụ na ha zutere ụkpụrụ nchekwa na ịdị irè. N'otu aka ahụ, Switzerland na-edobe ụkpụrụ nnabata ọgwụ siri ike n'okpuru Ụlọ Ọrụ Switzerland maka Ngwaahịa Ọgwụ (Swissmedic). Ndị ọrụ nchịkwa ndị a dị oke mkpa n'ịkpụzi usoro ahịa ahịa nke 3- (trifluoromethyl) phenylacetic acid ka ha na-emetụta ngwa ngwa nyocha na mmepe yana mmalite nke ngwaahịa ọhụrụ.
Ihe ịma aka ahịa
N'agbanyeghị atụmanya ya na-ekwe nkwa, ahịa 3- (trifluoromethyl) phenylacetic acid ka na-eche ụfọdụ ihe ịma aka ihu. Ihe mgbochi dị ịrịba ama bụ ọnụ ahịa dị elu nke nyocha na mmepe, nke nwere ike igbochi obere ụlọ ọrụ ịbanye n'ahịa. Na mgbakwunye, mgbagwoju anya nke imepụta ogige a na ịhụ na ịdị mma na-agbanwe agbanwe na-ebute ihe ịma aka nye ndị nrụpụta.
Na mgbakwunye, ụlọ ọrụ ọgwụ na-eto eto na-elekwasị anya na omume na-adigide yana omume enyi na gburugburu ebe obibi nwere ike imetụta usoro mmepụta nke 3- (trifluoromethyl) phenylacetic acid. A na-arụgide ụlọ ọrụ iji nweta teknụzụ na-acha akwụkwọ ndụ akwụkwọ ndụ, nke nwere ike ibute mgbanwe n'usoro ọkọnọ na usoro mmepụta.
atụmanya
Na-ele anya n'ihu, a na-atụ anya na ahịa 3- (trifluoromethyl) phenylacetic acid ga-eto na United States na Switzerland. Ọnụ ọgụgụ na-arịwanye elu nke ọrịa na-adịghị ala ala na mkpa ọgwụgwọ ọhụrụ na-akpalite ọchịchọ nke ogige ọgwụ ọhụrụ. Ka nyocha na-aga n'ihu na-ekpughe ngwa ndị nwere ike ime maka ogige a, anyị nwere ike ịhụ mmụba na ojiji ya na mmepe ọgwụ.
Na mgbakwunye, a na-atụ anya na mmekorita dị n'etiti ụlọ akwụkwọ agụmakwụkwọ na ụlọ ọrụ ọgwụ ga-eme ka mpaghara nyocha wee bute ngwa na usoro ọhụụ. Ilekwasị anya na ọgwụ ahaziri onwe ya na usoro ọgwụgwọ ezubere iche ga-emepụtakwa ohere ọhụrụ maka 3- (trifluoromethyl) phenylacetic acid, na-eme ka ọ bụrụ isi ihe na mmepe ọgwụ n'ọdịnihu.
Na nchịkọta, ahịa ọgwụ 3- (trifluoromethyl) phenylacetic acid dị na United States na Switzerland nọ n'ụzọ dị elu, nke ihe ọhụrụ, nkwado usoro iwu na-achọsi ike maka ọgwụgwọ ọgwụgwọ dị irè. Ka ụlọ ọrụ ahụ na-aga n'ihu na-etolite, ogige a nwere ike ịrụ ọrụ dị mkpa n'ịkpụzi ọdịnihu ọgwụ.
Oge nzipu: Ọktoba 30-2024