Sodium nitroprusside dihydrate (CAS# 13755-38-9)

Koodu ihe egwu	R25 - Na-egbu egbu ma ọ bụrụ na iloro ya R26/27/28 - Na-egbu egbu nke ukwuu site na iku ume, na kọntaktị na akpụkpọ ahụ ma ọ bụrụ na iloro ya.
Nkọwapụta nchekwa	S45 - Ọ bụrụ na ihe mberede ma ọ bụ ọ bụrụ na ahụ adịghị gị mma, chọọ ndụmọdụ ahụike ozugbo (gosi akara ahụ mgbe ọ bụla enwere ike.) S36 / 37/39 - Yiri uwe nchebe kwesịrị ekwesị, uwe aka na nchebe anya / ihu. S22 - Ekula uzuzu.
NJ UN	UN 3288 6.1/PG 3
WGK Germany	3
RTECS	LJ8925000
FLUKA BRAND F CODES	3
TSCA	Ee
Koodu HS	28372000
Klas Hazard	6.1
Otu nkwakọ ngwaahịa	III
Nsi	LD50 ọnụ na oke bekee: 99 mg / kg

Ntụaka Gosikwuo

1. Tian, ​​Ya-qin, et al. "Tụnyere usoro mmịpụta dị iche iche na njikarịcha nke ihe mgbakwunye microwave na-enyere aka…

Soluble na mmiri, ubé soluble na mmanya. Ngwọta mmiri ya adịghị eguzosi ike ma nwee ike jiri nwayọọ nwayọọ decompose ma tụgharịa akwụkwọ ndụ akwụkwọ ndụ.

okwu mmeghe	sodium nitroprusside (usoro ihe omimi: Na2 [Fe (CN) 5NO] · 2H2O, aha kemịkal: sodium nitroferricyanide dihydrate) bụ vasodilator na-eme ngwa ngwa na nke dị mkpụmkpụ, nke a na-eji ọgwụgwọ eme ihe maka ọbara mgbali elu mberede dị ka nsogbu hypertensive, hypertensive encephalopathy, ọbara mgbali elu na-adịghị mma, ọbara mgbali elu paroxysmal tupu na mgbe ịwa ahụ pheochromocytoma, wdg, a pụkwara iji ya mee ihe. hypotension a na-achịkwa n'oge ịwa ahụ.
mmetụta	sodium nitroprusside bụ vasodilator dị ike na-eme ngwa ngwa, nke nwere mmetụta dilation ozugbo na akwara akwara na akwara dị nro, na-ebelata nguzogide vaskụla site na ịgbasa arịa ọbara., Mepụta mmetụta antihypertensive. Mgbasa akwara nwekwara ike ibelata ibu tupu na mgbe obi gasịrị, melite mmepụta obi, ma belata reflux ọbara mgbe emechighị valvụ ahụ, nke mere na enwere ike iwepụ ihe mgbaàmà nke nkụda obi.
egosi	1. a na-eji ya maka mberede hypotension nke mberede ọbara mgbali elu, dị ka hypertensive hypertensive, hypertensive encephalopathy, malignant hypertension, paroxysmal hypertension tupu na mgbe pheochromocytoma ịwa ahụ, na nwekwara ike-eji maka hypotension na-achịkwa n'oge ịwa ahụ anesthesia. 2. Maka nnukwu obi mgbawa, gụnyere nnukwu edema akpa ume. A na-ejikwa ya maka nnukwu nkụchi obi na nnukwu myocardial infarction ma ọ bụ mgbe valvụ (mitral ma ọ bụ aortic valve) adịghị emechi.
pharmacokinetics	rute ọnụ ọgụgụ kachasị elu nke ọbara ozugbo ọ gbasasịrị eriri afọ, ọkwa ya dabere na dose ahụ. A na-emepụta ngwaahịa a site na mkpụrụ ndụ ọbara uhie n'ime cyanide, cyanide na imeju na-eme ka ọ bụrụ thiocyanate, na metabolite enweghị ọrụ vasodilating; cyanide nwekwara ike isonye na metabolism nke vitamin B12. Ngwaahịa a na-arụ ọrụ ihe fọrọ nke nta ka ọ bụrụ ozugbo nchịkwa gasịrị wee rute ọnụ ọgụgụ kachasị elu nke omume, ma na-edobe maka 1 ~ 10 nkeji mgbe nkwụsị nke eriri afọ. Ọkara ndụ nke ndị ọrịa nwere ọrụ gbasara akụrụ nkịtị bụ ụbọchị 7 (nke thiocyanate tụrụ ya), ogologo oge mgbe ọrụ akụrụ adịghị mma ma ọ bụ sodium ọbara dị ntakịrị, ma akụrụ na-ewepụ ya.
Usoro sịntetik maka ịkwadebe	sodium nitroprusside, gụnyere usoro ndị a: 1) Ịmepụta ọla kọpa nitroso ferrocyanide: na-agbakwunye mmiri dị ọcha kwesịrị ekwesị iji gbazee potassium nitroso-ferricyanide na tankị crystallization, kpo oku ruo 70-80 ℃ iji gbazee ya kpamkpam, ma jiri nwayọọ nwayọọ na-agbakwunye ọla kọpa sulfate pentahydrate. aqueous ngwọta dropwise, mgbe mmeghachi omume na-na-ekpo ọkụ 30 nkeji, centrifuge, na Achịcha nzacha centrifuged (ọla kọpa nitroso ferricyanide) etinyere n'ime tankị kristal. 2) sịntetik sodium nitroprusside (sodium nitronitroferricyanide): Kwadebe saturated sodium bicarbonate aqueous ngwọta dị ka ndepụta nri, ma jiri nwayọọ nwayọọ tinye ya na nitroso ferricyanide na 30-60 degrees C. Mgbe mmeghachi omume, centrifuge, na-anakọta filtrate na ude mmiri. 3) Ntinye uche na kristal: A na-ebunye ihe nzacha a na-anakọta na ude mmiri na tankị na-ekpo ọkụ, na glacial acetic acid na-eji nwayọọ nwayọọ na-agbakwunye ya ruo mgbe ọ dịghị ihe ọ bụla na-emepụta. Gbanyụọ mgbapụta na-ekpo ọkụ na ikpo ọkụ ruo 40-60 degrees C, malite ịta ahụhụ, tinye uche na ọnụ ọgụgụ buru ibu nke mmiri ozuzo kristal, mechie valvụ uzuoku, valvụ oghere iji kwadebe maka crystallization. 4) Centrifugal ihicha: mgbe crystallization gasịrị, a na-ewepụ ihe dị elu, kristal na-akpali akpali na centrifuged, a na-etinye achicha nzacha n'ime efere igwe anaghị agba nchara, a na-enwetakwa ngwaahịa ahụ site na ihicha oghere.
ọrụ ndu	Sodium Nitroprusside bụ vasodilator dị ike nke na-arụ ọrụ site n'iwepụta NO n'ime ọbara ozugbo.
Ebumnuche	Uru
Jiri	A na-eji ya dị ka reagent maka mkpebi nke aldehydes, ketones, sulfides, zinc, sulfur dioxide, wdg. Ejiri ya dị ka reagent maka mkpebi nke aldehydes, acetone, sulfur dioxide, zinc, Alkali metals, sulfides, wdg. Vasodilators. Nyocha nke aldehydes na ketones, zinc, sulfur dioxide na alkali metal sulfide. Nyocha chromatic, ule mmamịrị.