tert-butyl 2 4-dioxopiperidine-1-carboxylate (CAS # 845267-78-9)

Usoro ihe omimi	C10H15NO4
Molar Mass	213.23
Njupụta	1.199
Ebe Boling	373.8± 35.0 °C(buru amụma)
Ebe mgbari	179.9C
Uzuoku nrịbama	8.72E-06mmHg na 25°C
pKa	10.67± 0.20 (buru amụma)
Ọnọdụ Nchekwa	Debe n'ebe gbara ọchịchịrị, mechie ya na nkụ, okpomọkụ ụlọ
Ntụgharị uche	1.493
MDL	MFCD10566071

Nkọwa ngwaahịa

Koodu ihe egwu	20/21/22 - Na-emerụ ahụ site na iku ume, na kọntaktị na akpụkpọ ahụ ma ọ bụrụ na loro.
Nkọwapụta nchekwa	S23 - Ekula uzuoku. S24/25 - Zere kọntaktị na akpụkpọ ahụ na anya.
WGK Germany	3
Koodu HS	29337900

Jiri	2, 4-dipiperidon-1-formate tert-butyl formate bụ njikọ nke phenoxymethyl-dihydrothiazolopyridone mmepụta Reactants na ngwaahịa, dị ka a nhọrọ ziri ezi Ọdịdị modulator (PAM) nke metabolized glutamate 5 (mGlu5) nnabata.
ngwa	2, 4-dioperidone-1-tert-butyl formate bụ nke a na-ejikarị dị ka organic intermediate na pharmaceutical intermediate, na ike ga-eji na laabu nnyocha na mmepe usoro na chemical njikọ njikọ ọgwụ.
nkwadebe	nzọụkwụ a: tinye EDCI (191.7g) na DMF (400mL) ngwọta nke 3- (tert-butoxycarbonylamino) propionic acid (189.2g,1.0mol), meldamic acid (144.1g,1.0mol) na DMAP (135.0g,1.1mol). ) jụrụ oyi site na mmiri ịsa mmiri, 1.0mol). A kpalitere ndị reactant ndị a kpalitere n'otu abalị na okpomọkụ ụlọ. Emenyụ mmeghachi omume ahụ na 200ml H2O. Agbakwunyere ngwakọta nke sitere na dropwise na H2O(2.0L) n'okpuru mkpali igwe. A na-enyocha ihe siri ike enwetara ma jiri mmiri saa ya nke ọma na pH 7 iji nweta ngwaahịa (283g,90% mkpụrụ). Nzọụkwụ B: Ngwọta nke 3- (2, 2-dimethyl-4, 6-dioxo-1, 3-dioxan-5-yl) -3-oxopropylcarbamate tert-butyl ester (100g,317.46mmol) na toluene (1500mL) na-ekpo ọkụ na 100 ° C maka awa 4. The reactants na-mma na ụlọ okpomọkụ na lekwasị n'okpuru mbelata mgbali iji nweta a crude ngwaahịa. Ngwaahịa ahụ (mkpụrụ 56g,83%) bụ nke MTBE-egweri sachara.