Z-DL-ALA-OH (CAS# 4132-86-9)

Okwu mmalite

N-Carbobenzyloxy-DL-alanine bụ ngwakọta organic, nke a na-akpọkarị Cbz-DL-Ala. Nke a bụ nkọwa nke ọdịdị ya, ojiji ya, nhazi ya na ozi nchekwa:

Ọdịdị:

N-Carbobenzyloxy-DL-alanine bụ kristal na-acha ọcha siri ike nke nwere usoro ihe omimi nke C12H13NO4 yana oke molecular nke 235.24. Ọ nwere ụlọ ọrụ chiral abụọ ya mere ọ na-egosipụta isomers anya. Enwere ike ịgbaze ya n'ọtụtụ ihe mgbaze organic, dị ka mmanya na dimethylformamide. Ọ bụ ngwakọta nke kwụsiri ike ma sie ike ire ere.

Jiri:

N-Carbobenzyloxy-DL-alanine bụ ihe nrụpụta amino acid na-ejikarị eme ihe. Enwere ike iji ya na njikọ nke peptides na protein nke nwere ike jikọta otu carboxyl na amine site na mmeghachi omume condensation n'etiti amino acid iji mepụta agbụ peptide. Enwere ike iwepụ otu nchekwa N-benzyloxycarbonyl site na ọnọdụ kwesịrị ekwesị ka emechara mmeghachi omume iji weghachi nhazi amino acid mbụ.

Ụzọ nkwadebe:

A na-eme nkwadebe nke N-Carbobenzyloxy-DL-alanine site na iji N-benzyloxycarbonyl-alanine na ego kwesịrị ekwesị nke DCC (diisopropylcarbamate) na ihe mgbaze kwesịrị ekwesị. Mmeghachi omume dehydrates na-etolite ihe owuwu amide, nke a na-eme ka ọ dị ọcha site crystallization iji nye ngwaahịa a chọrọ.

Ozi nchekwa:

N-Carbobenzyloxy-DL-alanine na-adịkarị mma mgbe ejiri ya n'okpuru ọnọdụ ọrụ kwesịrị ekwesị. Agbanyeghị, ebe ọ bụ kemịkalụ, ntuziaka maka omume ụlọ nyocha dị mma ka kwesịrị ịgbaso. Ọ nwere ike ịkpasu anya na akpụkpọ ahụ iwe, yabụ na-eyi ihe nchekwa onwe gị kwesịrị ekwesị dịka uwe aka na enyo n'oge ị na-arụ ọrụ. Tụkwasị na nke ahụ, a ga-echekwa ya n'ebe kpọrọ nkụ, nke na-eku ume nke ọma, pụọ na ọkụ na ihe ndị na-ere ọkụ. Maka ozi ndị ọzọ gbasara njikwa na njikwa nchekwa ha, rụtụ aka na mpempe data nchekwa dị mkpa (SDS) nke kemịkalụ ma ọ bụ kpọtụrụ ọkachamara.